Juhana Karha, MD
Dr. Juhana Karha was born in Finland, raised in Chicago, and happy to now call Austin, Texas his home. He earned his undergraduate degree at the University of Chicago and went on to receive his medical degree from Northwestern University Medical School. Post-graduate training began with an Internal Medicine internship and residency from Brigham and Women’s Hospital at Harvard University. He completed a cardiovascular medicine and interventional cardiology fellowship at the Cleveland Clinic Foundation. Dr. Karha is the author of 23 peer-reviewed scientific publications and several cardiology textbooks.
He joined Austin Heart in 2008 specializing in Interventional Cardiology, Peripheral Vascular Intervention, PFO/ASD closure, Carotid Stenting, Structural Heart Intervention, such as mitral and pulmonic valvuloplasty, and the Transcatheter Aortic Valve Replacement (TAVR). Partnering with interventional cardiologist, Dr. Frank Zidar, and Cardiovascular and Thoracic Surgeons Drs. Stephen Dewan and Faraz Kerendi, they established the first Heart Valve Clinic in Central Texas located at the Heart Hospital of Austin, utilizing a new treatment in valve replacement, called TAVR. By collaboratively combining the skills and knowledge of both cardiovascular surgeons and interventional cardiologists, patients with valve disease now have a new treatment option.
Dr. Karha is board certified in internal medicine, interventional cardiology, and cardiovascular medicine. He is board certified in the interpretation of non-invasive vascular studies (RPVI) and certified in nuclear cardiology by the Certification Board of Nuclear Cardiology. He serves as Medical Director of the Heart Valve Clinic. Dr. Karha also serves as an Austin Heart CME committee member.
He and his wife have 3 children, 2 girls and a boy. When Dr. Karha is not providing care to his patients, he is enjoying sports and time with his family.
- Shishehbor MH, Lauer MS, Singh IM, Chew DP, Karha J, Brener SJ, Moliterno DJ, Ellis SG, Topol EJ, Bhatt DL. In unstable angina or non-ST-segment acute coronary syndrome, should patients with multivessel coronary artery disease undergo multivessel or culprit-only stenting? J Am Coll Cardiol 2007 Feb 27;49(8):849-54. Epub 2007 Feb 8.
- Exaire JE, Fathi RB, Brener SJ, Karha J, Ellis SG, Bhatt DL. Impaired myocardial perfusion score and inflammatory markers in patients undergoing primary angioplasty for acute myocardial infarction. Arch Cardiol Mex. 2006 Oct-Dec;76(4):376-82.
- Bavry AA, Chiu JH, Jefferson BK, Karha J, Bhatt DL, Ellis SG, Whitlow PL. Development of coronary aneurysm after drug-eluting stent implantation. Ann Intern Med. 2007 Feb 6;146(3):230-2.
- Doonan AL, Karha J, Carrigan TP, Bavry AA, Begelman SM, Ellis SG, Yadav J, Bhatt DL. Presense of carotid and peripheral arterial disease in patients with left main disease. Am J Cardiol. 2007 Oct 1; 100 (7): 1087-9. Epub 2007 Jul 18.
- Karha J, Gurm HS, Rajagopal V, Fathi R, Bavry AA, Brener SJ, Lincoff AM, Ellis SG, Bhatt DL. Use of platelet glycoprotein IIb/IIIa inhibitors in saphenous vein graft percutaneous coronary intervention and clinical outcomes. Am J Cardiol. 2006 Oct 1;98(7):906-10. Epub 2006 Aug 17.
- Karha J, Bavry AA, Rajagopal V, Henderson MR, Ellis SG, Brener SJ. Relation of C-reactive protein level and long-term risk of death or myocardial infarction following percutaneous coronary intervention with a sirolimus-eluting stent. Am J Cardiol. 2006 Sep 1;98(5):616-8. Epub 2006 Jul 10.
- Karha J, Rajagopal V, Kottke-Marchant K, Bhatt DL. Lack of effect of enteric coating on aspirin-induced inhibition of platelet aggregation in healthy volunteers. Am Heart J. 2006 May;151(5):976.e7-11.
- Karha J, Topol EJ. Primary percutaneous coronary intervention vs. fibrinolytic therapy for acute ST-elevation myocardial infarction in the elderly.Am J Geriatr Cardiol. 2006 Jan-Feb;15(1):19-21.
- Karha J, Hook MA, Brener SJ. Primary percutaneous coronary intervention for acute MI: improving access and outcomes. Cleve Clin J Med. 2005 Jul;72(7):559-60, 562, 565-6 passim.
- Karha J, Bhatt DL. Plaque regression - a new target for antiatherosclerotic therapy. Am Heart J. 2005 Mar; 149(3): 384-7.
- Karha J, Exaire JE, Rajagopal V, Ivanc TB, Kapadia SR, Ellis SG, Brener SJ. Relation of myocardial perfusion to mortality after primary percutaneous coronary intervention. Am J Cardiol. 2005 Apr 15;95(8):980-2.
- Karha J, Topol EJ. The sad story of Vioxx, and what we should learn from it. Cleve Clin J Med. 2004 Dec;71(12):933-4, 936, 938-9.
- Karha J, Gibson CM, Murphy SA, Dibattiste PM, Cannon CP; TIMI Study Group. Safety of stress testing during the evolution of unstable angina pectoris or non-ST-elevation myocardial infarction. Am J Cardiol. 2004 Dec 15;94(12):1537-9.
- Karha J, Bhatt DL. Percutaneous coronary intervention in diabetics. Rev Endocr Metab Disord. 2004 Aug;5(3):277-85.
- Gibson CM, Karha J, Giugliano RP, Roe MT, Murphy SA, Harrington RA, Green CL, Schweiger MJ, Miklin JS, Baran KW, Palmeri S, Braunwald E, Krucoff MW; INTEGRITI Study Group. Association of the timing of ST-segment resolution with TIMI myocardial perfusion grade in acute myocardial infarction. Am Heart J. 2004 May;147(5):847-52.
- Gibson CM, Karha J, Murphy SA, de Lemos JA, Morrow DA, Giugliano RP, Roe MT, Harrington RA, Cannon CP, Antman EM, Califf RM, Braunwald E; TIMI Study Group. Association of a pulsatile blood flow pattern on coronary arteriography and short-term clinical outcomes in acute myocardial infarction. J Am Coll Cardiol. 2004 Apr 7;43(7):1170-6.
- Gibson CM, Kirtane AJ, Murphy SA, Karha J, Cannon CP, Giugliano RP, Roe MT, Harrington RA, Ohman EM, Antman EM. Distance from the coronary ostium to the culprit lesion in acute ST-elevation myocardial infarction and its implications regarding the potential prevention of proximal plaque rupture. J Thromb Thrombolysis. 2003 Jun;15(3):189-96.
- Karha J, Murphy SA, Kirtane AJ, de Lemos JA, Aroesty JM, Cannon CP, Antman EM, Braunwald E, Gibson CM; TIMI Study Group. Evaluation of the association of proximal coronary culprit artery lesion location with clinical outcomes in acute myocardial infarction. Am J Cardiol. 2003 Oct 15;92(8):913-8.
- Gibson CM, Gibson WJ, Murphy SA, Marble SJ, McCabe CH, Turakhia MP, Kirtane AJ, Karha J, Aroesty JM, Giugliano RP, Antman EM; TIMI Study Group. Association of the Fibonacci Cascade with the distribution of coronary artery lesions responsible for ST-segment elevation myocardial infarction. Am J Cardiol. 2003 Sep 1;92(5):595-7.
- Gibson CM, Karha J, Murphy SA, James D, Morrow DA, Cannon CP, Giugliano RP, Antman EM, Braunwald E; TIMI Study Group. Early and long-term clinical outcomes associated with reinfarction following fibrinolytic administration in the Thrombolysis in Myocardial Infarction trials. J Am Coll Cardiol. 2003 Jul 2;42(1):7-16.
- Guerra DR, Karha J, Gibson CM. Safety and efficacy of tenecteplase in acute myocardial infarction. Expert Opin Pharmacother. 2003 May;4(5):791-8.
- Rankovic V, Karha J, Passman R, Kadish AH, Goldberger JJ. Predictors of appropriate implantable cardioverter-defibrillator therapy in patients with idiopathic dilated cardiomyopathy. Am J Cardiol. 2002 May 1;89(9):1072-6.
Abstracts in Medical Conferences:
- American Heart Association
- November 2006, Chicago. Karha J, Bhatt DL, Wolski K, Fox KAA, Montalescot G, Topol EJ. The Use of COX-2 Inhibitors and the Risk of Myocardial Infarction. Oral presentation.
- American Heart Association, November 2005, Dallas. Karha J, Chiu JH, Rajagopal V, Henderson MR, Ellis SG, Brener SJ. C-Reactive Protein Level and Long-Term Risk of Death or Myocardial Infarction Following Percutaneous Coronary Intervention with Sirolimus Eluting Stent. Oral presentation.
- The International Society on Thrombosis and Haemostasis XXth Congress, August 2005, Sydney, Australia. Karha J, Bhatt DL, Kottke-Marchant K. Use of PlateletworksTM vs. Arachidonic Acid Aggregation to Detect Aspirin Effect in Healthy Volunteers.
- American College of Cardiology, March 2005, Orlando. Karha J, Rajagopal V, Shishehbor MH, Ellis SG, Brener SJ. Multivessel Revascularization in the Setting of Primary Percutaneous Coronary Intervention for Acute ST- Elevation Myocardial Infarction. J Am Coll Cardiol 2005; 45 (Suppl. A): 201A.
- American College of Cardiology, March 2004, New Orleans. Karha J, Cannon CP, Murphy SA, DiBattiste PM, Gibson CM, Braunwald E. Safety of Stress Testing Following an Acute Coronary Syndrome. J Am Coll Cardiol 2004; 43 (Suppl. A): 277A.
- American College of Cardiology, March 2003, Chicago. Kirtane AJ, Murphy SA, Karha J, Wong GC, Giugliano RP, Antman EM, Gibson CM. A Mathematical Model of Preventing Plaque Rupture with Drug-Eluting Stents Based Upon the Distance from the Ostium to the Culprit Lesion in ST Elevation Myocardial Infarction. J Am Coll Cardiol 2003; 41 (Suppl. A): 20A.
- American College of Cardiology, March 2003, Chicago. Gibson CM, Karha J, Murphy SA, Cannon CP, Giugliano RP, Antman EM, Braunwald E. Percutaneous Coronary Intervention During the Index Hospitalization is Associated with Reduced Recurrent Myocardial Infarction and Improved Survival Following Thrombolytic Administration. J Am Coll Cardiol 2003; 41 (Suppl. A): 398A.
- American College of Cardiology, March 2003, Chicago. Karha J, Murphy SA, Kirtane AJ, Cannon CP, Antman EM, Gibson CM. Increased Risk of Adverse Outcomes with Proximal Culprit Artery Lesions in Acute Myocardial Infarction. J Am Coll Cardiol 2003; 41 (Suppl. A): 322A.
- Circadian and gender effects on repolarization in healthy adults: a study using harmonic regression analysis Mayuga KA, Thattassery E, Taneja T, Karha J, Subacius H, Goldberger J, Kadish A Ann Noninvasive Electrocardiol. 2010 Jan; 15 (1): 3-10
- “Study finds new source for heart disease prevention” (Your News Now, 11/11/2008, Austin, TX)
- “Taking care of your heart” (My Fox Austin, 7/3/2009, Austin, TX)
- “Nursing Professor Evelyn Clingerman” - July 2010 (NSIDE ATX, Austin, TX)
- “St. David's HealthCare to buy Heart Hospital of Austin” (American-Statesman, Austin, TX)
Medical Education & Training
Medical School: Northwestern University Medical School, Chicago, IL
Residency: Brighamaand Women's Hospital, Boston, MA
Fellowship: Cleveland Clinic Foundation, Cleveland, OH
Specialty Board Certifications: Internal Medicine, Interventional Cardiology, Nuclear Cardiology, Cardiovascular Disease
Juhana Karha, MD
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